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Circular RNA PVT1 Regulates Cell Proliferation, Migration, and Apoptosis by Stabilizing c-Myc and Downstream Target CXCR4 Expression in Acute Myeloid Leukemia

OBJECTIVE: This study aimed to investigate the role and mechanism of circular RNA PVT1 (circPVT1) in patients with acute myeloid leukemia (AML). MATERIALS AND METHODS: The expression of circPVT1 in 23 patients with de novo AML (not acute promyelocytic leukemia, not APL) and cell lines were detected...

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Detalles Bibliográficos
Autores principales: Sheng, Xian-Fu, Hong, Li-Li, Fan, Lei, Zhang, Yu, Chen, Kai-Li, Mu, Jie, Shen, Si-yu, Zhuang, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240161/
https://www.ncbi.nlm.nih.gov/pubmed/36718632
http://dx.doi.org/10.4274/tjh.galenos.2023.2022.0435