Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures

Adult autologous human epidermal stem cells can be extensively expanded ex vivo for cell and gene therapy. Identifying the mechanisms involved in stem cell maintenance and defining culture conditions to maintain stemness is critical, because an inadequate environment can result in the rapid conversi...

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Detalles Bibliográficos
Autores principales: Nanba, Daisuke, Sakabe, Jun‐Ichi, Mosig, Johannes, Brouard, Michel, Toki, Fujio, Shimokawa, Mariko, Kamiya, Mako, Braschler, Thomas, Azzabi, Fahd, Droz‐Georget Lathion, Stéphanie, Johnsson, Kai, Roy, Keya, Schmid, Christoph D, Bureau, Jean‐Baptiste, Rochat, Ariane, Barrandon, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240198/
https://www.ncbi.nlm.nih.gov/pubmed/37139607
http://dx.doi.org/10.15252/embr.202255439

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