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CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the management of aggressive hematologic malignancies. However, its role in patients with lymphoma and cardiac metastasis or cardiomyopathy remains undefined due to potentially life-threatening complications such as ventricular rupt...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240233/ https://www.ncbi.nlm.nih.gov/pubmed/37283829 http://dx.doi.org/10.1016/j.jaccas.2023.101840 |
| _version_ | 1785053706529538048 |
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| author | Ng, Choon Ta Gonzalez Bonilla, Hilda M. Chang, Ian Aung, M. Tun Gile, Jennifer J. Pereira, Naveen L. Villasboas Bisneto, Jose C. Johnston, Patrick B. Villarraga, Hector R. Rodriguez-Porcel, Martin G. Lin, Grace Lin, Yi Herrmann, Joerg |
| author_facet | Ng, Choon Ta Gonzalez Bonilla, Hilda M. Chang, Ian Aung, M. Tun Gile, Jennifer J. Pereira, Naveen L. Villasboas Bisneto, Jose C. Johnston, Patrick B. Villarraga, Hector R. Rodriguez-Porcel, Martin G. Lin, Grace Lin, Yi Herrmann, Joerg |
| author_sort | Ng, Choon Ta |
| collection | PubMed |
| description | Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the management of aggressive hematologic malignancies. However, its role in patients with lymphoma and cardiac metastasis or cardiomyopathy remains undefined due to potentially life-threatening complications such as ventricular rupture, cardiac tamponade, and circulatory failure. We present a case series of patients with lymphoma and cardiomyopathy or cardiac metastasis managed with chimeric antigen receptor T-cell therapy. (Level of Difficulty: Advanced.) |
| format | Online Article Text |
| id | pubmed-10240233 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102402332023-06-06 CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement Ng, Choon Ta Gonzalez Bonilla, Hilda M. Chang, Ian Aung, M. Tun Gile, Jennifer J. Pereira, Naveen L. Villasboas Bisneto, Jose C. Johnston, Patrick B. Villarraga, Hector R. Rodriguez-Porcel, Martin G. Lin, Grace Lin, Yi Herrmann, Joerg JACC Case Rep Mini-Focus Issue: Cardio-Oncology Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the management of aggressive hematologic malignancies. However, its role in patients with lymphoma and cardiac metastasis or cardiomyopathy remains undefined due to potentially life-threatening complications such as ventricular rupture, cardiac tamponade, and circulatory failure. We present a case series of patients with lymphoma and cardiomyopathy or cardiac metastasis managed with chimeric antigen receptor T-cell therapy. (Level of Difficulty: Advanced.) Elsevier 2023-04-21 /pmc/articles/PMC10240233/ /pubmed/37283829 http://dx.doi.org/10.1016/j.jaccas.2023.101840 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Mini-Focus Issue: Cardio-Oncology Ng, Choon Ta Gonzalez Bonilla, Hilda M. Chang, Ian Aung, M. Tun Gile, Jennifer J. Pereira, Naveen L. Villasboas Bisneto, Jose C. Johnston, Patrick B. Villarraga, Hector R. Rodriguez-Porcel, Martin G. Lin, Grace Lin, Yi Herrmann, Joerg CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title | CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title_full | CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title_fullStr | CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title_full_unstemmed | CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title_short | CAR-T Therapy in Lymphoma Patients With Coexisting Cardiomyopathy or Cardiac Lymphomatous Involvement |
| title_sort | car-t therapy in lymphoma patients with coexisting cardiomyopathy or cardiac lymphomatous involvement |
| topic | Mini-Focus Issue: Cardio-Oncology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240233/ https://www.ncbi.nlm.nih.gov/pubmed/37283829 http://dx.doi.org/10.1016/j.jaccas.2023.101840 |
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