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Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR
Using hybridized [(18)F]-fluorodeoxyglucose positron emission tomography with cardiac magnetic resonance, we identify active myocardial inflammation and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that late gadolinium enhancement represents, at lea...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240277/ https://www.ncbi.nlm.nih.gov/pubmed/37283843 http://dx.doi.org/10.1016/j.jaccas.2023.101863 |
| _version_ | 1785053715865010176 |
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| author | Orsborne, Christopher Anton-Rodrigez, Jose M. Sherratt, Neal Watkins, Amy Lohezic, Maelene Clark, David Lloyd, William Naish, Josephine H. Woolfson, Peter Reid, Anna B. Schmitt, Matthias Muthu, Sivakumar Arumugam, Parthiban Jovanovic, Ana Miller, Christopher A. |
| author_facet | Orsborne, Christopher Anton-Rodrigez, Jose M. Sherratt, Neal Watkins, Amy Lohezic, Maelene Clark, David Lloyd, William Naish, Josephine H. Woolfson, Peter Reid, Anna B. Schmitt, Matthias Muthu, Sivakumar Arumugam, Parthiban Jovanovic, Ana Miller, Christopher A. |
| author_sort | Orsborne, Christopher |
| collection | PubMed |
| description | Using hybridized [(18)F]-fluorodeoxyglucose positron emission tomography with cardiac magnetic resonance, we identify active myocardial inflammation and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that late gadolinium enhancement represents, at least in part, active myocardial inflammation and identify an early inflammatory phenotype that may represent a therapeutic window before irreversible tissue injury and adaptation occur. (Level of Difficulty: Intermediate.) |
| format | Online Article Text |
| id | pubmed-10240277 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102402772023-06-06 Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR Orsborne, Christopher Anton-Rodrigez, Jose M. Sherratt, Neal Watkins, Amy Lohezic, Maelene Clark, David Lloyd, William Naish, Josephine H. Woolfson, Peter Reid, Anna B. Schmitt, Matthias Muthu, Sivakumar Arumugam, Parthiban Jovanovic, Ana Miller, Christopher A. JACC Case Rep Mini-Focus Issue: Structural Heart Using hybridized [(18)F]-fluorodeoxyglucose positron emission tomography with cardiac magnetic resonance, we identify active myocardial inflammation and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that late gadolinium enhancement represents, at least in part, active myocardial inflammation and identify an early inflammatory phenotype that may represent a therapeutic window before irreversible tissue injury and adaptation occur. (Level of Difficulty: Intermediate.) Elsevier 2023-05-06 /pmc/articles/PMC10240277/ /pubmed/37283843 http://dx.doi.org/10.1016/j.jaccas.2023.101863 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Mini-Focus Issue: Structural Heart Orsborne, Christopher Anton-Rodrigez, Jose M. Sherratt, Neal Watkins, Amy Lohezic, Maelene Clark, David Lloyd, William Naish, Josephine H. Woolfson, Peter Reid, Anna B. Schmitt, Matthias Muthu, Sivakumar Arumugam, Parthiban Jovanovic, Ana Miller, Christopher A. Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title | Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title_full | Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title_fullStr | Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title_full_unstemmed | Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title_short | Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [(18)F]-FDG PET-CMR |
| title_sort | inflammatory fabry cardiomyopathy demonstrated using simultaneous [(18)f]-fdg pet-cmr |
| topic | Mini-Focus Issue: Structural Heart |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240277/ https://www.ncbi.nlm.nih.gov/pubmed/37283843 http://dx.doi.org/10.1016/j.jaccas.2023.101863 |
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