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(5R)-5-hydroxytriptolide for HIV immunological non-responders receiving ART: a randomized, double-blinded, placebo-controlled phase II study

BACKGROUND: Therapeutic approaches to HIV-suppressed immunological non-responders (INRs) remain unsettled. We previously reported efficacy of Chinese herbal Tripterygium wilfordii Hook F in INRs. Its derivative (5R)-5-hydroxytriptolide (LLDT-8) on CD4 T cell recovery was assessed. METHODS: The phase...

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Detalles Bibliográficos
Autores principales:	Cao, Wei, Liu, Xiaosheng, Han, Yang, Song, Xiaojing, Lu, Lianfeng, Li, Xiaodi, Lin, Ling, Sun, Lijun, Liu, An, Zhao, Hongxin, Han, Ning, Wei, Hongxia, Cheng, Jian, Zhu, Biao, Wang, Min, Li, Ying, Ma, Ping, Gao, Liying, Wang, Xicheng, Yu, Jianhua, Zhu, Ting, Routy, Jean-Pierre, Zuo, Min, Li, Taisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240372/ https://www.ncbi.nlm.nih.gov/pubmed/37283977 http://dx.doi.org/10.1016/j.lanwpc.2023.100724

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