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Nakaseomyces glabrata endocarditis: A therapeutic dilemma

Candida infective endocarditis is a rare but serious entity that often requires aggressive treatment. However, treatment can be challenging in patients infected with drug-resistant fungi and/or with substantial comorbidity. Moreover, recommendations in treatment guidelines for these patients are bas...

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Autores principales: Jim, Kin Ki, Daems, Joelle J.N., Boekholdt, S. Matthijs, van Dijk, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240517/
https://www.ncbi.nlm.nih.gov/pubmed/37283717
http://dx.doi.org/10.1016/j.mmcr.2023.04.002
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author Jim, Kin Ki
Daems, Joelle J.N.
Boekholdt, S. Matthijs
van Dijk, Karin
author_facet Jim, Kin Ki
Daems, Joelle J.N.
Boekholdt, S. Matthijs
van Dijk, Karin
author_sort Jim, Kin Ki
collection PubMed
description Candida infective endocarditis is a rare but serious entity that often requires aggressive treatment. However, treatment can be challenging in patients infected with drug-resistant fungi and/or with substantial comorbidity. Moreover, recommendations in treatment guidelines for these patients are based on limited clinical data due to their rarity. Here we report a case of Nakaseomyces glabrata (Candida glabrata) prosthetic valve endocarditis in a patient with congenital heart disease. This case illustrates a therapeutic dilemma for Nakaseomyces glabrata prosthetic valve endocarditis and the need for novel antifungal drugs and further clinical studies.
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spelling pubmed-102405172023-06-06 Nakaseomyces glabrata endocarditis: A therapeutic dilemma Jim, Kin Ki Daems, Joelle J.N. Boekholdt, S. Matthijs van Dijk, Karin Med Mycol Case Rep Case Report Candida infective endocarditis is a rare but serious entity that often requires aggressive treatment. However, treatment can be challenging in patients infected with drug-resistant fungi and/or with substantial comorbidity. Moreover, recommendations in treatment guidelines for these patients are based on limited clinical data due to their rarity. Here we report a case of Nakaseomyces glabrata (Candida glabrata) prosthetic valve endocarditis in a patient with congenital heart disease. This case illustrates a therapeutic dilemma for Nakaseomyces glabrata prosthetic valve endocarditis and the need for novel antifungal drugs and further clinical studies. Elsevier 2023-04-28 /pmc/articles/PMC10240517/ /pubmed/37283717 http://dx.doi.org/10.1016/j.mmcr.2023.04.002 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Jim, Kin Ki
Daems, Joelle J.N.
Boekholdt, S. Matthijs
van Dijk, Karin
Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title_full Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title_fullStr Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title_full_unstemmed Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title_short Nakaseomyces glabrata endocarditis: A therapeutic dilemma
title_sort nakaseomyces glabrata endocarditis: a therapeutic dilemma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240517/
https://www.ncbi.nlm.nih.gov/pubmed/37283717
http://dx.doi.org/10.1016/j.mmcr.2023.04.002
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