Germline ATM Mutations Detected by Somatic DNA Sequencing in Lethal Prostate Cancer

BACKGROUND: Germline mutations in the ataxia telangiectasia mutated (ATM) gene occur in 0.5–1% of the overall population and are associated with tumour predisposition. The clinical and pathological features of ATM-mutated prostate cancer (PC) are poorly defined but have been associated with lethal P...

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Detalles Bibliográficos
Autores principales: Grochot, Rafael, Carreira, Suzanne, Miranda, Susana, Figueiredo, Ines, Bertan, Claudia, Rekowski, Jan, Yuan, Wei, Ferreira, Ana, Riisnaes, Ruth, Neeb, Antje, Gurel, Bora, de Los Dolores Fenor de la Maza, Maria, Guo, Christina, Carmichael, Juliet, Westaby, Daniel, Mateo, Joaquin, Sharp, Adam, McVeigh, Terri P., De Bono, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Prostate Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240520/
https://www.ncbi.nlm.nih.gov/pubmed/37284046
http://dx.doi.org/10.1016/j.euros.2023.04.003

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