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Recombinant factor IX Fc prophylaxis reduces pain and increases levels of physical activity, with sustained, long-term improvements in patients with hemophilia B: post hoc analysis of phase III trials using patient-reported outcomes

BACKGROUND: Pain is a common symptom of hemophilia that may adversely affect patients’ quality of life (QoL). Previous post hoc analyses of prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) have been published for adults and adolescents, demonstrating improvements in health-related Q...

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Detalles Bibliográficos
Autores principales: Astermark, Jan, Hermans, Cédric, Ezzalfani, Monia, Sidhom, Alaeddine, Barbier, Sylvaine, Kragh, Nana, Falk, Aletta, Eriksson, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240555/
https://www.ncbi.nlm.nih.gov/pubmed/37283819
http://dx.doi.org/10.1177/20406207231170701