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Recombinant factor IX Fc prophylaxis reduces pain and increases levels of physical activity, with sustained, long-term improvements in patients with hemophilia B: post hoc analysis of phase III trials using patient-reported outcomes
BACKGROUND: Pain is a common symptom of hemophilia that may adversely affect patients’ quality of life (QoL). Previous post hoc analyses of prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) have been published for adults and adolescents, demonstrating improvements in health-related Q...
Autores principales: | Astermark, Jan, Hermans, Cédric, Ezzalfani, Monia, Sidhom, Alaeddine, Barbier, Sylvaine, Kragh, Nana, Falk, Aletta, Eriksson, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240555/ https://www.ncbi.nlm.nih.gov/pubmed/37283819 http://dx.doi.org/10.1177/20406207231170701 |
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