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Integrated fecal microbiota and metabolomics analysis of the orlistat intervention effect on polycystic ovary syndrome rats induced by letrozole combined with a high-fat diet

BACKGROUND: This study aimed to compare the characteristics of the gut microbiota and their metabolite profiles between polycystic ovary syndrome (PCOS) and orlistat-treated PCOS rats (ORL-PCOS), which could help to better understand the underlying mechanism of the effect of orlistat on PCOS. METHOD...

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Detalles Bibliográficos
Autores principales:	Yang, Jianmei, Wang, Enli, Jiang, Mingmin, Tan, Yujun, Yao, Fangfang, Sun, Chenghong, Pan, Lihong, Gao, Ling, Yao, Jingchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240724/ https://www.ncbi.nlm.nih.gov/pubmed/37277785 http://dx.doi.org/10.1186/s13048-023-01193-3

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