Correlation between KRAS and NRAS mutational status and clinicopathological features in 414 cases of metastatic colorectal cancer in Morocco: the largest North African case series

BACKGROUND: Advances in molecular biology have improved understanding of the molecular features of carcinogenesis and progression of colorectal cancer. It is clear that the efficacy of anti-EGFR depends upon the RAS mutational status, since any mutation in RAS is associated with resistance to anti-E...

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Detalles Bibliográficos
Autores principales: Mahdi, Youssef, Khmou, Mouna, Souadka, Amine, Agouri, Hajar El, Ech-charif, Soumaya, Mounjid, Chaimaa, Khannoussi, Basma El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240782/
https://www.ncbi.nlm.nih.gov/pubmed/37277698
http://dx.doi.org/10.1186/s12876-023-02694-7

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