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Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma
Benign and malignant orbital tumours develop from the orbit or invade it from the surrounding tissues. Ocular melanoma is a rare but potentially devastating malignancy arising from the melanocytes of the uveal tract, conjunctiva, or orbit. The poor overall survival depends mainly on its high metasta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240850/ https://www.ncbi.nlm.nih.gov/pubmed/37284226 http://dx.doi.org/10.1177/2050313X231173786 |
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author | Lalmand, Martin Gilis, Sarah Raptos, Alexandros Simon, Aurelien Van Brussel, Sara Sasserath, Christophe |
author_facet | Lalmand, Martin Gilis, Sarah Raptos, Alexandros Simon, Aurelien Van Brussel, Sara Sasserath, Christophe |
author_sort | Lalmand, Martin |
collection | PubMed |
description | Benign and malignant orbital tumours develop from the orbit or invade it from the surrounding tissues. Ocular melanoma is a rare but potentially devastating malignancy arising from the melanocytes of the uveal tract, conjunctiva, or orbit. The poor overall survival depends mainly on its high metastatic rate. Signs and symptoms are variables mainly depending on the size of the tumour. Its treatment consists generally of surgery, radiotherapy or both. We report a case of a patient suffering from unilateral blindness for the last 10 years with a recent swelling of the orbit. The pathological analysis described a uveal melanoma. The patient benefitted from a total orbital exenteration with reconstruction using a temporal flap. Thereafter, the patient received adjuvant radiotherapy and immunotherapy. The patient was in complete remission. No recurrence was highlighted after 2 years of follow-up. |
format | Online Article Text |
id | pubmed-10240850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-102408502023-06-06 Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma Lalmand, Martin Gilis, Sarah Raptos, Alexandros Simon, Aurelien Van Brussel, Sara Sasserath, Christophe SAGE Open Med Case Rep Case Report Benign and malignant orbital tumours develop from the orbit or invade it from the surrounding tissues. Ocular melanoma is a rare but potentially devastating malignancy arising from the melanocytes of the uveal tract, conjunctiva, or orbit. The poor overall survival depends mainly on its high metastatic rate. Signs and symptoms are variables mainly depending on the size of the tumour. Its treatment consists generally of surgery, radiotherapy or both. We report a case of a patient suffering from unilateral blindness for the last 10 years with a recent swelling of the orbit. The pathological analysis described a uveal melanoma. The patient benefitted from a total orbital exenteration with reconstruction using a temporal flap. Thereafter, the patient received adjuvant radiotherapy and immunotherapy. The patient was in complete remission. No recurrence was highlighted after 2 years of follow-up. SAGE Publications 2023-05-29 /pmc/articles/PMC10240850/ /pubmed/37284226 http://dx.doi.org/10.1177/2050313X231173786 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Lalmand, Martin Gilis, Sarah Raptos, Alexandros Simon, Aurelien Van Brussel, Sara Sasserath, Christophe Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title | Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title_full | Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title_fullStr | Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title_full_unstemmed | Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title_short | Ten years’ blindness of the right eye: A rare presentation of an orbital melanoma |
title_sort | ten years’ blindness of the right eye: a rare presentation of an orbital melanoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240850/ https://www.ncbi.nlm.nih.gov/pubmed/37284226 http://dx.doi.org/10.1177/2050313X231173786 |
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