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The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy

TERF2/TRF2 is a pleiotropic telomeric protein that plays a crucial role in tumor formation and progression through several telomere-dependent and -independent mechanisms. Here, we uncovered a novel function for this protein in regulating the macroautophagic/autophagic process upon different stimuli....

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Detalles Bibliográficos
Autores principales: Iachettini, Sara, Ciccarone, Fabio, Maresca, Carmen, D’ Angelo, Carmen, Petti, Eleonora, Di Vito, Serena, Ciriolo, Maria Rosa, Zizza, Pasquale, Biroccio, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240986/
https://www.ncbi.nlm.nih.gov/pubmed/36310382
http://dx.doi.org/10.1080/15548627.2022.2138687