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L‐BAIBA Synergizes with Sub‐Optimal Mechanical Loading to Promote New Bone Formation

The L‐enantiomer of β‐aminoisobutyric acid (BAIBA) is secreted by contracted muscle in mice, and exercise increases serum levels in humans. In mice, L‐BAIBA reduces bone loss with unloading, but whether it can have a positive effect with loading is unknown. Since synergism can be more easily observe...

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Detalles Bibliográficos
Autores principales: Prideaux, Matt, Smargiassi, Alberto, Peng, Gang, Brotto, Marco, Robling, Alexander G, Bonewald, Lynda F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241089/
https://www.ncbi.nlm.nih.gov/pubmed/37283651
http://dx.doi.org/10.1002/jbm4.10746