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Amiloidosis cardíaca: reporte de caso
Amyloidosis is a multisystem disease caused by infiltration of misfolded proteins; cardiac involvement determines its prognosis. There are several types of precursor proteins capable of causing the disease; however, only two affect the heart, clonal immunoglobulin light chains (AL) and tetrameric tr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Nacional Cardiovascular - INCOR
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241331/ https://www.ncbi.nlm.nih.gov/pubmed/37283604 http://dx.doi.org/10.47487/apcyccv.v3i2.207 |
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author | Viñas-Mendieta, Adriana E. García-Saavedra, Mario B. |
author_facet | Viñas-Mendieta, Adriana E. García-Saavedra, Mario B. |
author_sort | Viñas-Mendieta, Adriana E. |
collection | PubMed |
description | Amyloidosis is a multisystem disease caused by infiltration of misfolded proteins; cardiac involvement determines its prognosis. There are several types of precursor proteins capable of causing the disease; however, only two affect the heart, clonal immunoglobulin light chains (AL) and tetrameric transthyretin (TTR) protein. It is an underdiagnosed disease and, in late stages, it has a poor prognosis. We present the case of an older adult patient with progressive cardiac and extracardiac manifestations, as well as laboratory and echocardiographic criteria that brought us closer to the diagnosis of cardiac amyloidosis and also allowed us to assess the prognosis. The patient had a torpid evolution with a fatal outcome. The pathological anatomy studies allowed us to confirm our diagnostic presumption. |
format | Online Article Text |
id | pubmed-10241331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Instituto Nacional Cardiovascular - INCOR |
record_format | MEDLINE/PubMed |
spelling | pubmed-102413312023-06-05 Amiloidosis cardíaca: reporte de caso Viñas-Mendieta, Adriana E. García-Saavedra, Mario B. Arch Peru Cardiol Cir Cardiovasc Reporte De Caso Amyloidosis is a multisystem disease caused by infiltration of misfolded proteins; cardiac involvement determines its prognosis. There are several types of precursor proteins capable of causing the disease; however, only two affect the heart, clonal immunoglobulin light chains (AL) and tetrameric transthyretin (TTR) protein. It is an underdiagnosed disease and, in late stages, it has a poor prognosis. We present the case of an older adult patient with progressive cardiac and extracardiac manifestations, as well as laboratory and echocardiographic criteria that brought us closer to the diagnosis of cardiac amyloidosis and also allowed us to assess the prognosis. The patient had a torpid evolution with a fatal outcome. The pathological anatomy studies allowed us to confirm our diagnostic presumption. Instituto Nacional Cardiovascular - INCOR 2022-06-27 /pmc/articles/PMC10241331/ /pubmed/37283604 http://dx.doi.org/10.47487/apcyccv.v3i2.207 Text en https://creativecommons.org/licenses/by-nc/4.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons |
spellingShingle | Reporte De Caso Viñas-Mendieta, Adriana E. García-Saavedra, Mario B. Amiloidosis cardíaca: reporte de caso |
title | Amiloidosis cardíaca: reporte de caso |
title_full | Amiloidosis cardíaca: reporte de caso |
title_fullStr | Amiloidosis cardíaca: reporte de caso |
title_full_unstemmed | Amiloidosis cardíaca: reporte de caso |
title_short | Amiloidosis cardíaca: reporte de caso |
title_sort | amiloidosis cardíaca: reporte de caso |
topic | Reporte De Caso |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241331/ https://www.ncbi.nlm.nih.gov/pubmed/37283604 http://dx.doi.org/10.47487/apcyccv.v3i2.207 |
work_keys_str_mv | AT vinasmendietaadrianae amiloidosiscardiacareportedecaso AT garciasaavedramariob amiloidosiscardiacareportedecaso |