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Deep self-supervised learning for biosynthetic gene cluster detection and product classification
Natural products are chemical compounds that form the basis of many therapeutics used in the pharmaceutical industry. In microbes, natural products are synthesized by groups of colocalized genes called biosynthetic gene clusters (BGCs). With advances in high-throughput sequencing, there has been an...
Autores principales: | Rios-Martinez, Carolina, Bhattacharya, Nicholas, Amini, Ava P., Crawford, Lorin, Yang, Kevin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241353/ https://www.ncbi.nlm.nih.gov/pubmed/37220151 http://dx.doi.org/10.1371/journal.pcbi.1011162 |
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