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Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda

Measuring quality of life is a key component in the management of Chronic Obstructive Pulmonary Disease (COPD). The COPD assessment test (CAT), an easy to administer and shorter instrument than the standard Saint George’s respiratory questionnaire (SGRQ), could be an alternative tool for measuring t...

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Autores principales: Batte, Charles, Semulimi, Andrew Weil, Mutebi, Ronald Kasoma, Twinamasiko, Nelson, Muyama, Sarah Racheal, Mukisa, John, Atukunda, Immaculate, Mukunya, David, Kalyesubula, Robert, Trishul, Siddharthan, Kirenga, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241354/
https://www.ncbi.nlm.nih.gov/pubmed/37276227
http://dx.doi.org/10.1371/journal.pgph.0002013
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author Batte, Charles
Semulimi, Andrew Weil
Mutebi, Ronald Kasoma
Twinamasiko, Nelson
Muyama, Sarah Racheal
Mukisa, John
Atukunda, Immaculate
Mukunya, David
Kalyesubula, Robert
Trishul, Siddharthan
Kirenga, Bruce
author_facet Batte, Charles
Semulimi, Andrew Weil
Mutebi, Ronald Kasoma
Twinamasiko, Nelson
Muyama, Sarah Racheal
Mukisa, John
Atukunda, Immaculate
Mukunya, David
Kalyesubula, Robert
Trishul, Siddharthan
Kirenga, Bruce
author_sort Batte, Charles
collection PubMed
description Measuring quality of life is a key component in the management of Chronic Obstructive Pulmonary Disease (COPD). The COPD assessment test (CAT), an easy to administer and shorter instrument than the standard Saint George’s respiratory questionnaire (SGRQ), could be an alternative tool for measuring the quality of life of COPD patients in rural Uganda. A cross-sectional study was conducted between June and August 2022, consecutively recruiting 113 COPD patients aged > 40 years from the Low-Dose Theophylline for the management of Biomass-associated COPD (LODOT-BCOPD) study. Upon obtaining consent, participants answered an interviewer administered social demographic, CAT and SGRQ questionnaire. Internal consistency for both SGRQ and CAT was determined using Cronbach’s alpha coefficient and values > 0.7 were considered acceptable while correlations were determined using Spearman’s rank correlation. Limits of Agreement were visualised using Bland Altman and pair plots. Of the 113 participants, 51 (45.1%) were female. The mean age was 64 ± 12 years, 19 (16.8%) had history of smoking while majority (112 (99.1%)) reported use of firewood for cooking. There was a strong correlation of 0.791 (p < 0.001) between the CAT and SGRQ total scores with a high internal consistency of CAT, Cronbach’s alpha coefficient of 0.924 (0.901–0.946). The agreement between the absolute CAT scores and the SGRQ scores was good with a mean difference of -0.932 (95% Confidence Interval: -33.49–31.62). In summary, CAT has an acceptable validity and can be used as an alternative to the SGRQ to assess the quality of life of COPD patients in rural Uganda.
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spelling pubmed-102413542023-06-06 Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda Batte, Charles Semulimi, Andrew Weil Mutebi, Ronald Kasoma Twinamasiko, Nelson Muyama, Sarah Racheal Mukisa, John Atukunda, Immaculate Mukunya, David Kalyesubula, Robert Trishul, Siddharthan Kirenga, Bruce PLOS Glob Public Health Research Article Measuring quality of life is a key component in the management of Chronic Obstructive Pulmonary Disease (COPD). The COPD assessment test (CAT), an easy to administer and shorter instrument than the standard Saint George’s respiratory questionnaire (SGRQ), could be an alternative tool for measuring the quality of life of COPD patients in rural Uganda. A cross-sectional study was conducted between June and August 2022, consecutively recruiting 113 COPD patients aged > 40 years from the Low-Dose Theophylline for the management of Biomass-associated COPD (LODOT-BCOPD) study. Upon obtaining consent, participants answered an interviewer administered social demographic, CAT and SGRQ questionnaire. Internal consistency for both SGRQ and CAT was determined using Cronbach’s alpha coefficient and values > 0.7 were considered acceptable while correlations were determined using Spearman’s rank correlation. Limits of Agreement were visualised using Bland Altman and pair plots. Of the 113 participants, 51 (45.1%) were female. The mean age was 64 ± 12 years, 19 (16.8%) had history of smoking while majority (112 (99.1%)) reported use of firewood for cooking. There was a strong correlation of 0.791 (p < 0.001) between the CAT and SGRQ total scores with a high internal consistency of CAT, Cronbach’s alpha coefficient of 0.924 (0.901–0.946). The agreement between the absolute CAT scores and the SGRQ scores was good with a mean difference of -0.932 (95% Confidence Interval: -33.49–31.62). In summary, CAT has an acceptable validity and can be used as an alternative to the SGRQ to assess the quality of life of COPD patients in rural Uganda. Public Library of Science 2023-06-05 /pmc/articles/PMC10241354/ /pubmed/37276227 http://dx.doi.org/10.1371/journal.pgph.0002013 Text en © 2023 Batte et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Batte, Charles
Semulimi, Andrew Weil
Mutebi, Ronald Kasoma
Twinamasiko, Nelson
Muyama, Sarah Racheal
Mukisa, John
Atukunda, Immaculate
Mukunya, David
Kalyesubula, Robert
Trishul, Siddharthan
Kirenga, Bruce
Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title_full Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title_fullStr Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title_full_unstemmed Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title_short Cross-sectional validation of the COPD Assessment Test (CAT) among chronic obstructive pulmonary disease patients in rural Uganda
title_sort cross-sectional validation of the copd assessment test (cat) among chronic obstructive pulmonary disease patients in rural uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241354/
https://www.ncbi.nlm.nih.gov/pubmed/37276227
http://dx.doi.org/10.1371/journal.pgph.0002013
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