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Investigation on the binding behavior of human α1-acid glycoprotein with Janus Kinase inhibitor baricitinib: Multi-spectroscopic and molecular simulation methodologies

Baricitinib is a Janus Kinase (JAK) inhibitor that is primarily used to treat moderately to severely active rheumatoid arthritis in adults and has recently been reported for the treatment of patients with severe COVID-19. This paper describes the investigation of the binding behavior of baricitinib...

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Detalles Bibliográficos
Autores principales: Jiang, Shao-Liang, Hu, Zhe-Ying, Wang, Wan-Jun, Hu, Lu, Li, Li, Kou, Song-Bo, Shi, Jie-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241657/
https://www.ncbi.nlm.nih.gov/pubmed/37285878
http://dx.doi.org/10.1016/j.ijbiomac.2023.125096