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Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer

BACKGROUND: ESR1 mutations have been identified as mechanism for endocrine resistance and are also associated with a decreased overall survival. We assessed ESR1 mutations in circulating tumor DNA (ctDNA) for impact on outcome to taxane-based chemotherapy in advanced breast cancer patients. METHODS:...

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Detalles Bibliográficos
Autores principales:	Bos, M. K., Lam, S. W., Motta, G., Helmijr, J. C. A., Beaufort, C. M., de Jonge, E., Martens, J. W. M., Boven, E., Jansen, M. P. H. M., Jager, A., Sleijfer, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241671/ https://www.ncbi.nlm.nih.gov/pubmed/37226020 http://dx.doi.org/10.1007/s10549-023-06965-5

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