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Quantification of subtype purity in Luminal A breast cancer predicts clinical characteristics and survival

PURPOSE: PAM50 profiling assigns each breast cancer to a single intrinsic subtype based on a bulk tissue sample. However, individual cancers may show evidence of admixture with an alternate subtype that could affect prognosis and treatment response. We developed a method to model subtype admixture u...

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Detalles Bibliográficos
Autores principales:	Kumar, Neeraj, Gann, Peter H., McGregor, Stephanie M., Sethi, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241706/ https://www.ncbi.nlm.nih.gov/pubmed/37209182 http://dx.doi.org/10.1007/s10549-023-06961-9

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