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Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography

Photoacoustic tomography (PAT), also known as optoacoustic tomography, is an attractive imaging modality that provides optical contrast with acoustic resolutions. Recent progress in the applications of PAT largely relies on the development and employment of ultrasound sensor arrays with many element...

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Autores principales: Pan, Jingshun, Li, Qiang, Feng, Yaoming, Zhong, Ruifeng, Fu, Zhihao, Yang, Shuixian, Sun, Weiyuan, Zhang, Bin, Sui, Qi, Chen, Jun, Shen, Yuecheng, Li, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241812/
https://www.ncbi.nlm.nih.gov/pubmed/37277353
http://dx.doi.org/10.1038/s41467-023-39075-3
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author Pan, Jingshun
Li, Qiang
Feng, Yaoming
Zhong, Ruifeng
Fu, Zhihao
Yang, Shuixian
Sun, Weiyuan
Zhang, Bin
Sui, Qi
Chen, Jun
Shen, Yuecheng
Li, Zhaohui
author_facet Pan, Jingshun
Li, Qiang
Feng, Yaoming
Zhong, Ruifeng
Fu, Zhihao
Yang, Shuixian
Sun, Weiyuan
Zhang, Bin
Sui, Qi
Chen, Jun
Shen, Yuecheng
Li, Zhaohui
author_sort Pan, Jingshun
collection PubMed
description Photoacoustic tomography (PAT), also known as optoacoustic tomography, is an attractive imaging modality that provides optical contrast with acoustic resolutions. Recent progress in the applications of PAT largely relies on the development and employment of ultrasound sensor arrays with many elements. Although on-chip optical ultrasound sensors have been demonstrated with high sensitivity, large bandwidth, and small size, PAT with on-chip optical ultrasound sensor arrays is rarely reported. In this work, we demonstrate PAT with a chalcogenide-based micro-ring sensor array containing 15 elements, while each element supports a bandwidth of 175 MHz (−6 dB) and a noise-equivalent pressure of 2.2 mPaHz(−1/2). Moreover, by synthesizing a digital optical frequency comb (DOFC), we further develop an effective means of parallel interrogation to this sensor array. As a proof of concept, parallel interrogation with only one light source and one photoreceiver is demonstrated for PAT with this sensor array, providing images of fast-moving objects, leaf veins, and live zebrafish. The superior performance of the chalcogenide-based micro-ring sensor array and the effectiveness of the DOFC-enabled parallel interrogation offer great prospects for advancing applications in PAT.
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spelling pubmed-102418122023-06-07 Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography Pan, Jingshun Li, Qiang Feng, Yaoming Zhong, Ruifeng Fu, Zhihao Yang, Shuixian Sun, Weiyuan Zhang, Bin Sui, Qi Chen, Jun Shen, Yuecheng Li, Zhaohui Nat Commun Article Photoacoustic tomography (PAT), also known as optoacoustic tomography, is an attractive imaging modality that provides optical contrast with acoustic resolutions. Recent progress in the applications of PAT largely relies on the development and employment of ultrasound sensor arrays with many elements. Although on-chip optical ultrasound sensors have been demonstrated with high sensitivity, large bandwidth, and small size, PAT with on-chip optical ultrasound sensor arrays is rarely reported. In this work, we demonstrate PAT with a chalcogenide-based micro-ring sensor array containing 15 elements, while each element supports a bandwidth of 175 MHz (−6 dB) and a noise-equivalent pressure of 2.2 mPaHz(−1/2). Moreover, by synthesizing a digital optical frequency comb (DOFC), we further develop an effective means of parallel interrogation to this sensor array. As a proof of concept, parallel interrogation with only one light source and one photoreceiver is demonstrated for PAT with this sensor array, providing images of fast-moving objects, leaf veins, and live zebrafish. The superior performance of the chalcogenide-based micro-ring sensor array and the effectiveness of the DOFC-enabled parallel interrogation offer great prospects for advancing applications in PAT. Nature Publishing Group UK 2023-06-05 /pmc/articles/PMC10241812/ /pubmed/37277353 http://dx.doi.org/10.1038/s41467-023-39075-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pan, Jingshun
Li, Qiang
Feng, Yaoming
Zhong, Ruifeng
Fu, Zhihao
Yang, Shuixian
Sun, Weiyuan
Zhang, Bin
Sui, Qi
Chen, Jun
Shen, Yuecheng
Li, Zhaohui
Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title_full Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title_fullStr Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title_full_unstemmed Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title_short Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
title_sort parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241812/
https://www.ncbi.nlm.nih.gov/pubmed/37277353
http://dx.doi.org/10.1038/s41467-023-39075-3
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