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Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity

Innate immune responses vary by pathogen and host genetics. We analyze quantitative trait loci (eQTLs) and transcriptomes of monocytes from 215 individuals stimulated by fungal, Gram-negative or Gram-positive bacterial pathogens. We identify conserved monocyte responses to bacterial pathogens and a...

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Detalles Bibliográficos
Autores principales:	Häder, Antje, Schäuble, Sascha, Gehlen, Jan, Thielemann, Nadja, Buerfent, Benedikt C., Schüller, Vitalia, Hess, Timo, Wolf, Thomas, Schröder, Julia, Weber, Michael, Hünniger, Kerstin, Löffler, Jürgen, Vylkova, Slavena, Panagiotou, Gianni, Schumacher, Johannes, Kurzai, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241821/ https://www.ncbi.nlm.nih.gov/pubmed/37277347 http://dx.doi.org/10.1038/s41467-023-38994-5

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