Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female

• Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential. • Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy. • Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a col...

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Detalles Bibliográficos
Autores principales: O'Connell, Cailin, Jang, Sylvia, Monroig-Bosque, Paloma, Alaniz, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241837/
https://www.ncbi.nlm.nih.gov/pubmed/37288348
http://dx.doi.org/10.1016/j.gore.2023.101207
Descripción
Sumario:• Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential. • Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy. • Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a collision tumor. • Alpha-fetoprotein can be trended over time to gauge response to treatment of cancers that produce the protein.

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