Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female

• Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential. • Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy. • Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a col...

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Autores principales: O'Connell, Cailin, Jang, Sylvia, Monroig-Bosque, Paloma, Alaniz, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241837/
https://www.ncbi.nlm.nih.gov/pubmed/37288348
http://dx.doi.org/10.1016/j.gore.2023.101207
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author O'Connell, Cailin
Jang, Sylvia
Monroig-Bosque, Paloma
Alaniz, Anne
author_facet O'Connell, Cailin
Jang, Sylvia
Monroig-Bosque, Paloma
Alaniz, Anne
author_sort O'Connell, Cailin
collection PubMed
description • Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential. • Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy. • Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a collision tumor. • Alpha-fetoprotein can be trended over time to gauge response to treatment of cancers that produce the protein.
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spelling pubmed-102418372023-06-07 Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female O'Connell, Cailin Jang, Sylvia Monroig-Bosque, Paloma Alaniz, Anne Gynecol Oncol Rep Case Report • Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential. • Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy. • Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a collision tumor. • Alpha-fetoprotein can be trended over time to gauge response to treatment of cancers that produce the protein. Elsevier 2023-05-25 /pmc/articles/PMC10241837/ /pubmed/37288348 http://dx.doi.org/10.1016/j.gore.2023.101207 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
O'Connell, Cailin
Jang, Sylvia
Monroig-Bosque, Paloma
Alaniz, Anne
Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title_full Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title_fullStr Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title_full_unstemmed Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title_short Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
title_sort cracking the case: the diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241837/
https://www.ncbi.nlm.nih.gov/pubmed/37288348
http://dx.doi.org/10.1016/j.gore.2023.101207
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