Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors

BACKGROUND: Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates in non-lymphoid tissues, which are associated with improved prognosis in some cancer types. This study aimed to investigate the clinical significance of TLSs in oesophageal cancer (EC). METHODS: In a series of 316 EC sur...

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Detalles Bibliográficos
Autores principales: Hayashi, Yoshinori, Makino, Tomoki, Sato, Eiichi, Ohshima, Kenji, Nogi, Yuya, Kanemura, Takashi, Honma, Keiichiro, Yamashita, Kotaro, Saito, Takuro, Tanaka, Koji, Yamamoto, Kazuyoshi, Takahashi, Tsuyoshi, Kurokawa, Yukinori, Miyata, Hiroshi, Nakajima, Kiyokazu, Wada, Hisashi, Morii, Eiichi, Eguchi, Hidetoshi, Doki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241865/
https://www.ncbi.nlm.nih.gov/pubmed/37016103
http://dx.doi.org/10.1038/s41416-023-02235-9

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