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C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A

C11orf54 is an ester hydrolase highly conserved across different species. C11orf54 has been identified as a biomarker protein of renal cancers, but its exact function remains poorly understood. Here we demonstrate that C11orf54 knockdown decreases cell proliferation and enhances cisplatin-induced DN...

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Detalles Bibliográficos
Autores principales: Tan, Junyang, Wang, Wenjun, Liu, Xinjie, Xu, Jinhong, Che, Yaping, Liu, Yanyan, Hu, Jiaqiao, Hu, Liubing, Li, Jianshuang, Zhou, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241914/
https://www.ncbi.nlm.nih.gov/pubmed/37277441
http://dx.doi.org/10.1038/s42003-023-04957-1

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