Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model

With Varicella-Zoster Virus (VZV) being an exclusive human pathogen, human induced pluripotent stem cell (hiPSC)-derived neural cell culture models are an emerging tool to investigate VZV neuro-immune interactions. Using a compartmentalized hiPSC-derived neuronal model allowing axonal VZV infection,...

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Detalles Bibliográficos
Autores principales: Van Breedam, Elise, Buyle-Huybrecht, Tamariche, Govaerts, Jonas, Meysman, Pieter, Bours, Andrea, Boeren, Marlies, Di Stefano, Julia, Caers, Thalissa, De Reu, Hans, Dirkx, Laura, Schippers, Jolien, Bartholomeus, Esther, Lebrun, Marielle, Sadzot-Delvaux, Catherine, Rybakowska, Paulina, Alarcón-Riquelme, Marta E., Marañón, Concepción, Laukens, Kris, Delputte, Peter, Ogunjimi, Benson, Ponsaerts, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241998/
https://www.ncbi.nlm.nih.gov/pubmed/37287975
http://dx.doi.org/10.3389/fimmu.2023.1177245

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