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A CRISPR-Cas12a-based platform for ultrasensitive rapid highly specific detection of Mycobacterium tuberculosis in clinical application

Tuberculosis, caused by Mycobacterium tuberculosis (MTB), is the second leading cause of death after COVID-19 pandemic. Here, we coupled multiple cross displacement amplification (MCDA) technique with CRISPR-Cas12a-based biosensing system to design a novel detection platform for tuberculosis diagnos...

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Detalles Bibliográficos
Autores principales:	Jia, Nan, Wang, Chaohong, Liu, Xiaming, Huang, Xiaolan, Xiao, Fei, Fu, Jin, Sun, Chunrong, Xu, Zheng, Wang, Guirong, Zhou, Juan, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242030/ https://www.ncbi.nlm.nih.gov/pubmed/37287467 http://dx.doi.org/10.3389/fcimb.2023.1192134

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