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Exhaustion of CD8(+) central memory responder T cell differentiation provokes non-melanoma skin cancer in elderly kidney transplant recipients

INTRODUCTION: Immunosuppressive therapy prevents graft rejection but increases the risk of non-melanoma skin cancer (NMSC), especially in elderly kidney transplant recipients (KTR). METHODS: In this study, we separately investigated the differentiation of CD8(+) regulatory T cells (Tregs) and respon...

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Detalles Bibliográficos
Autores principales:	Leonhard, Jonas, Schaier, Matthias, Kälble, Florian, Zeier, Martin, Steinborn, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242110/ https://www.ncbi.nlm.nih.gov/pubmed/37287988 http://dx.doi.org/10.3389/fimmu.2023.1164284

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