Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro

Genetic polymorphism of the cytochrome P450 (CYP) gene can significantly influence the metabolism of endogenous and xenobiotic compounds. However, few studies have focused on the polymorphism of CYP2J2 and its impact on drug catalytic activity, especially in the Chinese Han population. In this study...

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Detalles Bibliográficos
Autores principales: Zou, Li-Li, Zhao, Fang-Ling, Qi, Yu-Ying, Wang, Shuang-Hu, Zhou, Quan, Geng, Pei-Wu, Zhou, Yun-Fang, Zhang, Qing, Chen, Hao, Dai, Da-Peng, Cai, Jian-Ping, Ji, Fu-Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242136/
https://www.ncbi.nlm.nih.gov/pubmed/37288113
http://dx.doi.org/10.3389/fphar.2023.1186824

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