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cGAMP the travelling messenger

2’3’-cGAMP is a key molecule in the cGAS-STING pathway. This cyclic dinucleotide is produced by the cytosolic DNA sensor cGAS in response to the presence of aberrant dsDNA in the cytoplasm which is associated with microbial invasion or cellular damage. 2’3’-cGAMP acts as a second messenger and activ...

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Detalles Bibliográficos
Autores principales:	Blest, Henry T. W., Chauveau, Lise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242147/ https://www.ncbi.nlm.nih.gov/pubmed/37287967 http://dx.doi.org/10.3389/fimmu.2023.1150705

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