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GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

SARS-CoV-2 has resulted in high levels of morbidity and mortality world-wide, and severe complications can occur in older populations. Humoral immunity induced by authorized vaccines wanes within 6 months, and frequent boosts may only offer transient protection. GRT-R910 is an investigational self-a...

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Detalles Bibliográficos
Autores principales: Palmer, Christine D., Scallan, Ciaran D., Kraemer Tardif, Lauren D., Kachura, Melissa A., Rappaport, Amy R., Koralek, Daniel O., Uriel, Alison, Gitlin, Leonid, Klein, Joshua, Davis, Matthew J., Venkatraman, Harshni, Hart, Meghan G., Jaroslavsky, Jason R., Kounlavouth, Sonia, Marrali, Martina, Nganje, Charmaine N., Bae, Kyounghwa, Yan, Tiffany, Leodones, Katharyn, Egorova, Milana, Hong, Sue-Jean, Kuan, Jenchun, Grappi, Silvia, Garbes, Pedro, Jooss, Karin, Ustianowski, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242235/
https://www.ncbi.nlm.nih.gov/pubmed/37280238
http://dx.doi.org/10.1038/s41467-023-39053-9