Cargando…

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

SARS-CoV-2 has resulted in high levels of morbidity and mortality world-wide, and severe complications can occur in older populations. Humoral immunity induced by authorized vaccines wanes within 6 months, and frequent boosts may only offer transient protection. GRT-R910 is an investigational self-a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palmer, Christine D., Scallan, Ciaran D., Kraemer Tardif, Lauren D., Kachura, Melissa A., Rappaport, Amy R., Koralek, Daniel O., Uriel, Alison, Gitlin, Leonid, Klein, Joshua, Davis, Matthew J., Venkatraman, Harshni, Hart, Meghan G., Jaroslavsky, Jason R., Kounlavouth, Sonia, Marrali, Martina, Nganje, Charmaine N., Bae, Kyounghwa, Yan, Tiffany, Leodones, Katharyn, Egorova, Milana, Hong, Sue-Jean, Kuan, Jenchun, Grappi, Silvia, Garbes, Pedro, Jooss, Karin, Ustianowski, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242235/ https://www.ncbi.nlm.nih.gov/pubmed/37280238 http://dx.doi.org/10.1038/s41467-023-39053-9

Ejemplares similares

2346. Preliminary results of durable immune response induced by a self-amplifying mRNA (samRNA) SARS-CoV-2 vaccine candidate, GRT-R910, in adults previously vaccinated with mRNA or AZD1222 primary series
por: Uriel, Alison, et al.
Publicado: (2023)

2372. Preliminary evidence of durable immune responses induced by self-amplifying mRNA (samRNA) vaccine candidates against SARS-CoV-2 in vaccine-naive South African population
por: Koen, A, et al.
Publicado: (2023)

2395. An Interim Report of the Safety, Reactogenicity, and Immunogenicity of a Self-amplifying mRNA (samRNA) COVID-19 Vaccine GRT-R910 as a Booster in Healthy Adults
por: Whitaker, Jennifer, et al.
Publicado: (2023)

Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection
por: Rappaport, Amy R., et al.
Publicado: (2022)

Impaired Development of Somatotropes, Lactotropes and Thyrotropes in Growth-Retarded (grt) Mice
por: Kobayashi, Kenichi, et al.
Publicado: (2009)

Clinical Implications of TiGRT Algorithm for External Audit in Radiation Oncology
por: Shahbazi-Gahrouei, Daryoush, et al.
Publicado: (2017)

In vitro and in vivo hepatotoxicity study of Afriplex™ GRT through an inflammatory response
por: Gabuza, Kwazikwakhe B., et al.
Publicado: (2022)

9,10-Dimethyl-9,10-peroxy-9,10-dihydroanthracene
por: Wang, Yun-Wu
Publicado: (2008)

Oral Modeling of an Adenovirus-Based Quadrivalent Influenza Vaccine in Ferrets and Mice
por: Scallan, Ciaran D., et al.
Publicado: (2016)

9,10-Diiodophenanthrene
por: Yokota, Ruri, et al.
Publicado: (2012)

9,10-Dibromophenanthrene
por: Yokota, Ruri, et al.
Publicado: (2012)

4-(9,10-Dioxo-9,10-dihydroanthracen-1-yl)-4-oxobutanoic acid
por: Li, Yi, et al.
Publicado: (2010)

9,10-Dioxo-9,10-dihydroanthracene-1,4-diyl diacetate
por: Zhang, Jing-Jing, et al.
Publicado: (2013)

1,3-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carbaldehyde
por: Awang, Khalijah, et al.
Publicado: (2008)

N,N′-Diphenyl-9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonamide
por: Yuan, Wei-Guan, et al.
Publicado: (2013)

Facile Microwave-assisted Synthesis of 9,10-Dihydro-9,10-ethanoanthracene-11-carboxylic acid Methyl Ester
por: Phutdhawong, Weerachai, et al.
Publicado: (2005)

Ferrocenyl‐Pyrenes, Ferrocenyl‐9,10‐Phenanthrenediones, and Ferrocenyl‐9,10‐Dimethoxyphenanthrenes: Charge‐Transfer Studies and SWCNT Functionalization
por: Preuß, Andrea, et al.
Publicado: (2020)

Non-intuitive clustering of 9,10-phenanthrenequinone on Au(111)
por: Brown, Ryan D, et al.
Publicado: (2017)

9,9-Dimethyl-9,10-dihydroanthracene
por: Siddaraju, B. P., et al.
Publicado: (2011)

1-Dimethylamino-9,10-anthraquinone
por: Niedziałkowski, Paweł, et al.
Publicado: (2011)

Structural data of phenanthrene-9,10-dicarbonitriles
por: Afanasenko, Anastasiia M., et al.
Publicado: (2019)

A phase I clinical study to assess safety and immunogenicity of yellow fever vaccine
por: Desai, Sajjad, et al.
Publicado: (2022)

N-(12-Amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-4-methylbenzenesulfonamide
por: Mague, Joel T., et al.
Publicado: (2014)

Crystal structure of 9,10-bis(1,3-dithiol-2-ylidene)-9,10-dihydroanthracene
por: Ren, Yi, et al.
Publicado: (2015)

Synthesis of 2-(9,10-Dihydro-9,10-propanoanthracen-9-yl)-N-methylethanamine via a [4+2] Cycloaddition
por: Karama, Usama, et al.
Publicado: (2010)

2,6-Dimethoxy-9,10-anthraquinone
por: Ohta, Akira, et al.
Publicado: (2012)

1-(Piperidin-1-yl)-9,10-anthraquinone
por: Wnuk, Elżbieta, et al.
Publicado: (2012)

Mechanism for the photodegradation of 9,10-dibutoxyanthracene in the presence of air
por: Seto, Ryotaro, et al.
Publicado: (2022)

9,10-Bis(iodoethynyl)anthracene
por: Antoine, Nehemiah, et al.
Publicado: (2023)

910. Herpes Zoster in Children: A Literature Review
por: Simpson, Chris, et al.
Publicado: (2023)

9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine
por: Pattison, Graham, et al.
Publicado: (2010)

11-Hydroxy-9-(prop-2-en-1-yl)-9,10-dihydro-9,10-propanoanthracen-12-one
por: Karama, Usama, et al.
Publicado: (2011)

A Three‐Dimensional Inorganic Analogue of 9,10‐Diazido‐9,10‐Diboraanthracene: A Lewis Superacidic Azido Borane with Reactivity and Stability
por: Zhang, Chonghe, et al.
Publicado: (2022)

Health Uninsurance in rural America: a partial equilibrium analysis
por: Nganje, William, et al.
Publicado: (2019)

Bis(1,10-phenanthrolin-1-ium) 9,10-dioxo-9,10-dihydroanthracene-1,5-disulfonate hexahydrate
por: Jia, Jia
Publicado: (2011)

Self-Reported Real-World Safety and Reactogenicity of COVID-19 Vaccines: A Vaccine Recipient Survey
por: Mathioudakis, Alexander G., et al.
Publicado: (2021)

2-Formyl-3-hydroxy-9,10-anthroquinone
por: Ismail, Nor Hadiani, et al.
Publicado: (2008)

1-Methoxy-4-methyl-9,10-anthraquinone
por: Osman, Che Puteh, et al.
Publicado: (2011)

1,8-Bis(tosyloxy)-9,10-anthraquinone
por: Niedziałkowski, Paweł, et al.
Publicado: (2009)

Effect of 910-MHz Electromagnetic Field on Rat Bone Marrow
por: Demsia, George, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_dq0170s0bjeagddtu646h29atk