Cargando…

Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq

Sequencing the human genome empowers translational medicine, facilitating transcriptome‐wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are used to study the bulk transcriptome; but now short‐read RNA sequencing (RNA‐seq) predominates. Positioned as a superi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stokes, Tanner, Cen, Haoning Howard, Kapranov, Philipp, Gallagher, Iain J, Pitsillides, Andrew A., Volmar, Claude‐Henry, Kraus, William E, Johnson, James D., Phillips, Stuart M., Wahlestedt, Claes, Timmons, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242409/ https://www.ncbi.nlm.nih.gov/pubmed/37288167 http://dx.doi.org/10.1002/ggn2.202200024

Ejemplares similares

A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease
por: Timmons, James A, et al.
Publicado: (2018)

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease
por: Timmons, James A, et al.
Publicado: (2022)

Longevity‐related molecular pathways are subject to midlife “switch” in humans
por: Timmons, James A., et al.
Publicado: (2019)

Nucleic acid-based therapeutics for the treatment of central nervous system disorders
por: McCartan, Robyn, et al.
Publicado: (2023)

Amplifying gene expression with RNA-targeted therapeutics
por: Khorkova, Olga, et al.
Publicado: (2023)

Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research
por: Dennison, Jessica L., et al.
Publicado: (2021)

Natural antisense transcripts as drug targets
por: Khorkova, Olga, et al.
Publicado: (2022)

Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse
por: Dennison, Jessica, et al.
Publicado: (2023)

MicroScope: ChIP-seq and RNA-seq software analysis suite for gene expression heatmaps
por: Khomtchouk, Bohdan B., et al.
Publicado: (2016)

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL (TM))
por: Kemper, Christopher, et al.
Publicado: (2022)

Considerations when using the significance analysis of microarrays (SAM) algorithm
por: Larsson, Ola, et al.
Publicado: (2005)

Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients
por: Dennison, Jessica L., et al.
Publicado: (2022)

The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer’s Disease
por: Magistri, Marco, et al.
Publicado: (2016)

Emerging Technologies for Genome-Wide Profiling of DNA Breakage
por: Rybin, Matthew J., et al.
Publicado: (2021)

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
por: Stokes, Tanner, et al.
Publicado: (2020)

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma
por: Lohse, Ines, et al.
Publicado: (2018)

A statistical and biological response to an informatics appraisal of healthy aging gene signatures
por: Timmons, James A., et al.
Publicado: (2019)

Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia‐associated insulin resistance
por: Cen, Haoning Howard, et al.
Publicado: (2021)

Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells
por: Cao, Huifen, et al.
Publicado: (2019)

Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model
por: Janczura, Karolina J., et al.
Publicado: (2018)

Strangulation and Hanging
por: Templeman, Charles
Publicado: (1893)

Judicial Hanging
por: O'Gorman, P. W.
Publicado: (1894)

Science in Hanging
Publicado: (1870)

An End to Hanging
por: Parker, Tony
Publicado: (1970)

Strangulation and Hanging
por: Templeman, Charles
Publicado: (1893)

HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons
por: Bagheri, Amir, et al.
Publicado: (2019)

ASE Membership in the COVID-19 Pandemic: Hanging out, Hanging on, Together
por: Thamman, Ritu, et al.
Publicado: (2020)

A novel knockout mouse model of the noncoding antisense Brain-Derived Neurotrophic Factor (Bdnf) gene displays increased endogenous Bdnf protein and improved memory function following exercise
por: Modarresi, Farzaneh, et al.
Publicado: (2021)

Molecular studies of exercise, skeletal muscle, and ageing
por: Timmons, James A., et al.
Publicado: (2016)

Hanging Noncalculous Gallbladder
por: Tzardinoglou, E., et al.
Publicado: (1996)

Kinetochores hang on for the ride
por: Short, Ben
Publicado: (2010)

Notes on Judicial Hanging
por: Daley, F. J.
Publicado: (1908)

State of the Pericardium in Hanging
por: Higginson, F. W.
Publicado: (1875)

Cases of Death by Hanging
por: Cayley, H.
Publicado: (1873)

Experiments and Observations on Hanging
por: Casper,
Publicado: (1838)

Commentary: Hanging in the air
por: Shapira, Oz M.
Publicado: (2021)

How to Hang Pictures
Publicado: (1881)

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
por: Gallagher, Iain J, et al.
Publicado: (2010)

Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer’s Disease Models
por: Ricciardi, Natalie R., et al.
Publicado: (2023)

Hang cleans and hang snatches produce similar improvements in female collegiate athletes
por: Ayers, JL, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p7a5v6b6v1m2n9ob2lnaic21cl