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A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

Bacillus Calmette-Guérin (BCG) vaccination is a prototype model for the study of trained immunity (TI) in humans, and results in a more effective response of innate immune cells upon stimulation with heterologous stimuli. Here, we investigate the heterogeneity of TI induction by single-cell RNA sequ...

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Detalles Bibliográficos
Autores principales: Li, Wenchao, Moorlag, Simone J.C.F.M., Koeken, Valerie A.C.M., Röring, Rutger J., de Bree, L. Charlotte J., Mourits, Vera P., Gupta, Manoj K., Zhang, Bowen, Fu, Jianbo, Zhang, Zhenhua, Grondman, Inge, van Meijgaarden, Krista E., Zhou, Liang, Alaswad, Ahmed, Joosten, Leo A.B., van Crevel, Reinout, Xu, Cheng-Jian, Netea, Mihai G., Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242447/
https://www.ncbi.nlm.nih.gov/pubmed/37155329
http://dx.doi.org/10.1016/j.celrep.2023.112487

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