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Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice

BACKGROUND: SBP and blood pressure variability are independent risk factors for cerebral small vessel disease, a leading cause for stroke and dementia. Calcium-channel blockers are known to reduce blood pressure variability and may thus offer benefit against dementia. Beyond this effect, the impact...

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Detalles Bibliográficos
Autores principales:	Kerkhofs, Danielle, Helgers, Robin, Hermes, Denise, Steinbusch, Hellen P.J., Van Essen, Helma, Leenders, Peter, Prickaerts, Jos, Staals, Julie, Biessen, Erik A., Van Oostenbrugge, Robert J., Foulquier, Sébastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242521/ https://www.ncbi.nlm.nih.gov/pubmed/37071429 http://dx.doi.org/10.1097/HJH.0000000000003445

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