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Glycated albumin modulates the contact system with implications for the kallikrein-kinin and intrinsic coagulation systems
BACKGROUND: Human serum albumin (HSA) is the most abundant plasma protein and is sensitive to glycation in vivo. The chronic hyperglycemic conditions in patients with diabetes mellitus (DM) induce a nonenzymatic Maillard reaction that denatures plasma proteins and forms advanced glycation end produc...
Autores principales: | Hardy, Lewis J., Bohinc, Dillon, Bane, Kara L., Heal, Samantha L., Hethershaw, Emma, Ali, Majid, Palmer-Dench, Thomas, Foster, Richard, Longstaff, Colin, Renné, Thomas, Stavrou, Evi X., Philippou, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242648/ https://www.ncbi.nlm.nih.gov/pubmed/36990522 http://dx.doi.org/10.1016/j.jtha.2022.12.015 |
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