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Dissection of 3D chromosome organization in Streptomyces coelicolor A3(2) leads to biosynthetic gene cluster overexpression

The soil-dwelling filamentous bacteria, Streptomyces, is widely known for its ability to produce numerous bioactive natural products. Despite many efforts toward their overproduction and reconstitution, our limited understanding of the relationship between the host’s chromosome three dimension (3D)...

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Detalles Bibliográficos
Autores principales:	Deng, Liang, Zhao, Zhihu, Liu, Lin, Zhong, Zhiyu, Xie, Wenxinyu, Zhou, Fan, Xu, Wei, Zhang, Yubo, Deng, Zixin, Sun, Yuhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242723/ https://www.ncbi.nlm.nih.gov/pubmed/36877856 http://dx.doi.org/10.1073/pnas.2222045120

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