Cargando…

Identification and Verification of Key MiRNAs Associated with Intervertebral Disc Degeneration

BACKGROUND: Intervertebral Disc Degeneration (IDD) is a heterogeneous spinal disease whose underlying molecular mechanism is unclear. OBJECTIVES: This study aimed to identify, profile, and analyze microRNAs (miRNAs) related to IDD. METHODS: Microarray Gene Expression IDD data (GSE63492) were downloa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jianwei, Li, Rong, Lyv, Peizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2023
Materias:	Chemistry, Combinatorial Chemistry and High Throughput Screening, BIOCHEMICAL RESEARCH METHODS, Chemistry, APPLIED CHEMISTRY, Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242762/ https://www.ncbi.nlm.nih.gov/pubmed/36111773 http://dx.doi.org/10.2174/1386207325666220915113438

Ejemplares similares

Identification of Chemokines-Related miRNAs as Potential Biomarkers in Psoriasis Based on Integrated Bioinformatics Analysis
por: Zhuang, Haojun, et al.
Publicado: (2023)

Network Pharmacology-based Investigation of the Underlying Mechanism of Panax notoginseng Treatment of Diabetic Retinopathy
por: Piao, Chunli, et al.
Publicado: (2020)

Identification of Key Diagnostic Markers and Immune Infiltration in Osteoarthritis
por: Yan, Mingyue, et al.
Publicado: (2023)

Deep Learning for Predicting Distant Metastasis in Patients with Nasopharyngeal Carcinoma Based on Pre-Radiotherapy Magnetic Resonance Imaging
por: Hua, Hong-Li, et al.
Publicado: (2023)

HDL-Chitosan Nanoparticles for siRNA Delivery as an SR-B1 Receptor Targeted System
por: Masimov, Rasim, et al.
Publicado: (2023)

LincRNA-p21 Promotes Cellular Senescence by Down-regulating the Wnt/β-catenin Pathway in MPP(+)-treated SH-SY5Y Cells
por: Zhu, Jianyu, et al.
Publicado: (2023)

Pitongshu Alleviates the Adverse Symptoms in Rats with Functional Dyspepsia Through Regulating Visceral Hypersensitivity Caused by 5-HT Overexpression
por: Chen, Su-Hong, et al.
Publicado: (2023)

Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4
por: Rong, Baohai, et al.
Publicado: (2023)

Bridging Integrator 3 (BIN3) Downregulation Predicts a Poor Prognosis in Patients with Esophagus Carcinoma: A Study based on TCGA Data
por: Li, Daohang, et al.
Publicado: (2023)

Expression and Predictive Significance of FHL1 and SLIT3 in Surgically Resected Lung Adenocarcinoma
por: Song, Jinjing, et al.
Publicado: (2023)

Network Pharmacology Study on the Mechanism of Gastrodin Reversing Depressive Symptoms in Traumatically Stressed Rats
por: Zhao, Ruodan, et al.
Publicado: (2023)

Analysis of Pharmacological Activities and Mechanisms of Essential Oil in Leaves of C. grandis ‘Tomentosa’ by GC-MS/MS and Network Pharmacology
por: You, Jie-Shu, et al.
Publicado: (2023)

Dendrobium officinalis Six Nostrum Promotes Intestinal Urate Underexcretion via Regulations of Urate Transporter Proteins in Hyperuricemic Rats
por: Ge, Hongzhang, et al.
Publicado: (2023)

Penehyclidine Hydrochloride Protects Rat Cardiomyocytes from Ischemia-Reperfusion Injury by Platelet-derived Growth Factor-B
por: Lu, Yan, et al.
Publicado: (2023)

Exploring the Target and Mechanism of Radix Paeoniae Alba on Sjogren’s Syndrome
por: Wu, Fangping, et al.
Publicado: (2023)

Impact of Previous Pulmonary Tuberculosis on Chronic Obstructive Pulmonary Disease: Baseline Results from a Prospective Cohort Study
por: Wang, Yide, et al.
Publicado: (2023)

TIGIT as a Novel Prognostic Marker for Immune Infiltration in Invasive Breast Cancer
por: Guo, Chenming, et al.
Publicado: (2023)

Total Flavonoids from Rhizoma Drynariae (Gusuibu) Alleviates Diabetic Osteoporosis by Activating BMP2/Smad Signaling Pathway
por: Fang, Xin Hua, et al.
Publicado: (2023)

An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology
por: Gu, Sizhen, et al.
Publicado: (2020)

Molecular Mechanism of Caulis Spatholobi in the Treatment of Chronic Myeloid Leukemia based on Network Pharmacology and Experimental Verification
por: Wu, Yanchun, et al.
Publicado: (2023)

Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging
por: Mader, Kerstin T., et al.
Publicado: (2016)

Exploration of the Mechanism of Tripterygium Wilfordii in the Treatment of Myocardial Fibrosis Based on Network Pharmacology and Molecular Docking
por: Ming, Yang, et al.
Publicado: (2023)

Exploring the Molecular Mechanism of HongTeng Decoction against Inflammation based on Network Analysis and Experiments Validation
por: Yang, Yuanyuan, et al.
Publicado: (2023)

Network Pharmacology and Intestinal Microbiota Analysis Revealing the Mechanism of Punicalagin Improving Bacterial Enteritis
por: Huang, Shuyun, et al.
Publicado: (2023)

Potential Mechanisms Underlying the Therapeutic Roles of Gancao fuzi Decoction in Cold-dampness Obstruction Syndrome-type Knee Osteoarthritis
por: Zhao, Jinlong, et al.
Publicado: (2023)

Fabrication of a novel whole tissue-engineered intervertebral disc for intervertebral disc regeneration in the porcine lumbar spine
por: Yang, Fei, et al.
Publicado: (2018)

Comprehensive Analysis of Cuproptosis Genes and Identification of Cuproptosis Subtypes in Breast Cancer
por: Li, Jialin, et al.
Publicado: (2023)

Molecular Mechanisms of Notopterygii rhizoma Et Radix for Treating Arrhythmia Based on Network Pharmacology
por: Wei, Penglu, et al.
Publicado: (2023)

A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma
por: Lin, Lin, et al.
Publicado: (2023)

Injectable biomaterial induces regeneration of the intervertebral disc in a caprine loaded disc culture model
por: Snuggs, Joseph W., et al.
Publicado: (2023)

Peptide:glycosaminoglycan hybrid hydrogels as an injectable intervention for spinal disc degeneration
por: Miles, D. E., et al.
Publicado: (2016)

Allele-specific assembly of a eukaryotic genome corrects apparent frameshifts and reveals a lack of nonsense-mediated mRNA decay
por: Cosentino, Raúl O, et al.
Publicado: (2021)

Ideafix: a decision tree-based method for the refinement of variants in FFPE DNA sequencing data
por: Tellaetxe-Abete, Maitena, et al.
Publicado: (2021)

High-scale random access on DNA storage systems
por: El-Shaikh, Alex, et al.
Publicado: (2022)

Fast and memory-efficient mapping of short bisulfite sequencing reads using a two-letter alphabet
por: de Sena Brandine, Guilherme, et al.
Publicado: (2021)

iLoci: robust evaluation of genome content and organization for provisional and mature genome assemblies
por: Standage, Daniel S, et al.
Publicado: (2022)

Optocoder: computational decoding of spatially indexed bead arrays
por: Senel, Enes, et al.
Publicado: (2022)

Systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis
por: Johnson, Zachary, et al.
Publicado: (2022)

SIQ: easy quantitative measurement of mutation profiles in sequencing data
por: van Schendel, Robin, et al.
Publicado: (2022)

A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage
por: Li, Jianfeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eaa6r97eadpf4qmgkhb4qm2rut