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The winding roads to adulthood: A twin study

AIMS: Here we report the results of the first systematic investigation of genetic and environmental influences on 57 psychological traits covering major issues in emerging adulthood such as aspirations, thoughts and attitudes, relationships and personality. We also investigate how these traits relat...

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Autores principales: Rimfeld, Kaili, Malanchini, Margherita, Packer, Amy E., Gidziela, Agnieszka, Allegrini, Andrea G., Ayorech, Ziada, Smith‐Woolley, Emily, McMillan, Andrew, Ogden, Rachel, Dale, Philip S., Eley, Thalia C., Plomin, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242946/
https://www.ncbi.nlm.nih.gov/pubmed/37431409
http://dx.doi.org/10.1002/jcv2.12053
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author Rimfeld, Kaili
Malanchini, Margherita
Packer, Amy E.
Gidziela, Agnieszka
Allegrini, Andrea G.
Ayorech, Ziada
Smith‐Woolley, Emily
McMillan, Andrew
Ogden, Rachel
Dale, Philip S.
Eley, Thalia C.
Plomin, Robert
author_facet Rimfeld, Kaili
Malanchini, Margherita
Packer, Amy E.
Gidziela, Agnieszka
Allegrini, Andrea G.
Ayorech, Ziada
Smith‐Woolley, Emily
McMillan, Andrew
Ogden, Rachel
Dale, Philip S.
Eley, Thalia C.
Plomin, Robert
author_sort Rimfeld, Kaili
collection PubMed
description AIMS: Here we report the results of the first systematic investigation of genetic and environmental influences on 57 psychological traits covering major issues in emerging adulthood such as aspirations, thoughts and attitudes, relationships and personality. We also investigate how these traits relate to physical and mental health, educational attainment and wellbeing. MATERIALS & METHODS: We use a sample of nearly 5000 pairs of UK twins aged 21–25 from the Twins Early Development Study. We included 57 measures of traits selected to represent issues in emerging adulthood (EA) such as aspirations, thoughts and attitudes, life events, relationships, sexual and health behaviour and personality. We also included measures related to what are often considered to be the core functional outcomes even though here we refer to the data collected at the same time: adverse physical health, adverse mental health, wellbeing, and education. RESULTS: All 57 traits showed significant genetic influence, with an average heritability of 34% (SNP heritability ~10%). Most of the variance (59% on average) was explained by non‐shared environmental influences. These diverse traits were associated with mental health (average correlation 0.20), wellbeing (0.16), physical health (0.12) and educational attainment (0.06). Shared genetic factors explained the majority of these correlations (~50%). Together, these emerging adulthood traits explained on average 30% of variance in the outcomes (range = 8% to 69%), suggesting that these traits relate to the outcomes additively. DISCUSSION & CONCLUSIONS: We conclude that even as the majority of individual differences in EA traits is explained by non‐shared environmental factors, genetic influence on these traits is still substantial; the environmental uncertainties of emerging adulthood in the 21st century do not diminish the importance of genetics. As adolescents travel down long and winding roads to adulthood, their trip is substantially influenced by genetic proclivities that nudge them down different paths leading to different destinations.
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spelling pubmed-102429462023-07-10 The winding roads to adulthood: A twin study Rimfeld, Kaili Malanchini, Margherita Packer, Amy E. Gidziela, Agnieszka Allegrini, Andrea G. Ayorech, Ziada Smith‐Woolley, Emily McMillan, Andrew Ogden, Rachel Dale, Philip S. Eley, Thalia C. Plomin, Robert JCPP Adv Other Articles AIMS: Here we report the results of the first systematic investigation of genetic and environmental influences on 57 psychological traits covering major issues in emerging adulthood such as aspirations, thoughts and attitudes, relationships and personality. We also investigate how these traits relate to physical and mental health, educational attainment and wellbeing. MATERIALS & METHODS: We use a sample of nearly 5000 pairs of UK twins aged 21–25 from the Twins Early Development Study. We included 57 measures of traits selected to represent issues in emerging adulthood (EA) such as aspirations, thoughts and attitudes, life events, relationships, sexual and health behaviour and personality. We also included measures related to what are often considered to be the core functional outcomes even though here we refer to the data collected at the same time: adverse physical health, adverse mental health, wellbeing, and education. RESULTS: All 57 traits showed significant genetic influence, with an average heritability of 34% (SNP heritability ~10%). Most of the variance (59% on average) was explained by non‐shared environmental influences. These diverse traits were associated with mental health (average correlation 0.20), wellbeing (0.16), physical health (0.12) and educational attainment (0.06). Shared genetic factors explained the majority of these correlations (~50%). Together, these emerging adulthood traits explained on average 30% of variance in the outcomes (range = 8% to 69%), suggesting that these traits relate to the outcomes additively. DISCUSSION & CONCLUSIONS: We conclude that even as the majority of individual differences in EA traits is explained by non‐shared environmental factors, genetic influence on these traits is still substantial; the environmental uncertainties of emerging adulthood in the 21st century do not diminish the importance of genetics. As adolescents travel down long and winding roads to adulthood, their trip is substantially influenced by genetic proclivities that nudge them down different paths leading to different destinations. John Wiley and Sons Inc. 2021-12-11 /pmc/articles/PMC10242946/ /pubmed/37431409 http://dx.doi.org/10.1002/jcv2.12053 Text en © 2021 The Authors. JCPP Advances published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Other Articles
Rimfeld, Kaili
Malanchini, Margherita
Packer, Amy E.
Gidziela, Agnieszka
Allegrini, Andrea G.
Ayorech, Ziada
Smith‐Woolley, Emily
McMillan, Andrew
Ogden, Rachel
Dale, Philip S.
Eley, Thalia C.
Plomin, Robert
The winding roads to adulthood: A twin study
title The winding roads to adulthood: A twin study
title_full The winding roads to adulthood: A twin study
title_fullStr The winding roads to adulthood: A twin study
title_full_unstemmed The winding roads to adulthood: A twin study
title_short The winding roads to adulthood: A twin study
title_sort winding roads to adulthood: a twin study
topic Other Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242946/
https://www.ncbi.nlm.nih.gov/pubmed/37431409
http://dx.doi.org/10.1002/jcv2.12053
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