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Epiphany: predicting Hi-C contact maps from 1D epigenomic signals
Recent deep learning models that predict the Hi-C contact map from DNA sequence achieve promising accuracy but cannot generalize to new cell types and or even capture differences among training cell types. We propose Epiphany, a neural network to predict cell-type-specific Hi-C contact maps from wid...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242996/ https://www.ncbi.nlm.nih.gov/pubmed/37280678 http://dx.doi.org/10.1186/s13059-023-02934-9 |