NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway

BACKGROUND: Reprogramming lipid metabolism for tumor metastasis is essential in breast cancer, and NUCB2/Nesfatin-1 plays a crucial role in regulating energy metabolism. Its high expression is associated with poor prognosis in breast cancer. Here, we studied whether NUCB2/Nesfatin-1 promotes breast...

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Detalles Bibliográficos
Autores principales: Ning, Siyi, Liu, Caiying, Wang, Kangtao, Cai, Yubo, Ning, Zhicheng, Li, Ming, Zeng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243030/
https://www.ncbi.nlm.nih.gov/pubmed/37277807
http://dx.doi.org/10.1186/s12967-023-04236-x

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