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The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats

BACKGROUND: Hepatitis C virus (HCV) infection is a global public health problem and Egypt has the highest HCV prevalence worldwide. Hence, global efforts target to eliminate HCV by 2030. Sofosbuvir is a nucleotide analogue inhibitor of HCV polymerase essential for viral replication. Animal studies...

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Detalles Bibliográficos
Autores principales:	Mahmoud, Shimaa A., Abdel-Aziz, Maryam M., Khafaga, Rana H. M., Hafez, Hala A., Kamel, Maher A., Shaker, Sara A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243043/ https://www.ncbi.nlm.nih.gov/pubmed/37280507 http://dx.doi.org/10.1186/s10020-023-00666-x

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