Germline variants of uncertain significance, their frequency, and clinico-pathological features in a cohort of Sri Lankan patients with hereditary breast cancer

BACKGROUND: Next-Generation Sequencing (NGS)-based testing in cancer patients has led to increased detection of variants of uncertain significance (VUS). VUS are genetic variants whose impact on protein function is unknown. VUS pose a challenge to clinicians and patients due to uncertainty regarding...

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Detalles Bibliográficos
Autores principales: Gunawardena, Kawmadi, Sirisena, Nirmala D., Anandagoda, Gayani, Neththikumara, Nilaksha, Dissanayake, Vajira H.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243048/
https://www.ncbi.nlm.nih.gov/pubmed/37277882
http://dx.doi.org/10.1186/s13104-023-06365-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243048/
https://www.ncbi.nlm.nih.gov/pubmed/37277882
http://dx.doi.org/10.1186/s13104-023-06365-4

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