Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

[Image: see text] The DNA repair scaffold SLX4 has pivotal roles in cellular processes that maintain genome stability, most notably homologous recombination. Germline mutations in SLX4 are associated with Fanconi anemia, a disease characterized by chromosome instability and cancer susceptibility. Th...

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Autores principales: Aprosoff, Camila M., Dyakov, Boris J.A., Cheung, Vivian H.W., Wong, Cassandra J., Palandra, Mikaela, Gingras, Anne-Claude, Wyatt, Haley D.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243116/
https://www.ncbi.nlm.nih.gov/pubmed/37071664
http://dx.doi.org/10.1021/acs.jproteome.2c00706

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