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Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B(12) repair

Control over transition metal redox state is essential for metalloprotein function and can be achieved via coordination chemistry and/or sequestration from bulk solvent. Human methylmalonyl-Coenzyme A (CoA) mutase (MCM) catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA using 5′-deoxya...

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Detalles Bibliográficos
Autores principales:	Gouda, Harsha, Mascarenhas, Romila, Ruetz, Markus, Yaw, Madeline, Banerjee, Ruma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243129/ https://www.ncbi.nlm.nih.gov/pubmed/36888659 http://dx.doi.org/10.1073/pnas.2220677120

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