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Dissecting the energetic architecture within an RNA tertiary structural motif via high-throughput thermodynamic measurements

Structured RNAs and RNA/protein complexes perform critical cellular functions. They often contain structurally conserved tertiary contact “motifs,” whose occurrence simplifies the RNA folding landscape. Prior studies have focused on the conformational and energetic modularity of intact motifs. Here,...

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Detalles Bibliográficos
Autores principales: Shin, John H., Bonilla, Steve L., Denny, Sarah K., Greenleaf, William J., Herschlag, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243134/
https://www.ncbi.nlm.nih.gov/pubmed/36897989
http://dx.doi.org/10.1073/pnas.2220485120