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De Novo Linear Phosphorylation Site Motifs for BCR-ABL Kinase Revealed by Phospho-Proteomics in Yeast

[Image: see text] BCR-ABL is the oncogenic fusion product of tyrosine kinase ABL1 and a highly frequent driver of acute lymphocytic leukemia (ALL) and chronic myeloid leukemia (CML). The kinase activity of BCR-ABL is strongly elevated; however, changes of substrate specificity in comparison to wild-...

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Detalles Bibliográficos
Autores principales:	Smolnig, Martin, Fasching, Sandra, Stelzl, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243146/ https://www.ncbi.nlm.nih.gov/pubmed/37053475 http://dx.doi.org/10.1021/acs.jproteome.2c00795

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