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Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9‐based cellular model of VPS13A deficiency

VPS13A is a lipid transfer protein localized at different membrane contact sites between organelles, and mutations in the corresponding gene produce a rare neurodegenerative disease called chorea‐acanthocytosis (ChAc). Previous studies showed that VPS13A depletion in HeLa cells results in an accumul...

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Detalles Bibliográficos
Autores principales:	Tornero‐Écija, A. R., Navas, M. A., Muñoz‐Braceras, S., Vincent, O., Escalante, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243151/ https://www.ncbi.nlm.nih.gov/pubmed/37163371 http://dx.doi.org/10.1111/jcmm.17768

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