An interaction-based drug discovery screen explains known SARS-CoV-2 inhibitors and predicts new compound scaffolds

The recent outbreak of the COVID-19 pandemic caused by severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) has shown the necessity for fast and broad drug discovery methods to enable us to react quickly to novel and highly infectious diseases. A well-known SARS-CoV-2 target is the viral mai...

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Detalles Bibliográficos
Autores principales: Schake, Philipp, Dishnica, Klevia, Kaiser, Florian, Leberecht, Christoph, Haupt, V. Joachim, Schroeder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243268/
https://www.ncbi.nlm.nih.gov/pubmed/37280244
http://dx.doi.org/10.1038/s41598-023-35671-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243268/
https://www.ncbi.nlm.nih.gov/pubmed/37280244
http://dx.doi.org/10.1038/s41598-023-35671-x

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